Kantonsspital St.Gallen
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EORTC 1702-LCG-ROG Targeted therapy with or without dose-intensified radiotterapy in oligo-progressive disease (OPD) in oncogene Addicted Lung Tumors

Markus Glatzer

abstract

Targeted therapy beyond Progression with or without dose-intensified radiotHerapy in oligo-progressive disease (OPD) in oncogene Addicted Lung Tumors (HALT)

Objectives: To determine wether in patients with Mutation positive advanced NSCLC the use of SBRT to ≤ 3 sites of OPD with continuation of TKI improves Progression free survival (PFS) compared with continuation of TKI alone.

Target: 110 Patients for Phase II component
   
type of project clinical studies
status scheduled
start of project 2019
end of project 2025
study design Multicenter, Randomized Phase II / III Trial
responsible person Dr. Markus Glatzer