Unit
Kardiologie
KARDIO · Dept. I
Carity Study
Dec 1, 2023CARITY: A targeted approach to ensuring CARe and ActivITY persistence in mid- to older-age persons during and after cardiac rehabilitation following a cardiovascular event or intervention
Clinical Studies - Dec 1, 2023 - Feb 1, 2025
Ongoing
Project leader: Buser Marc
Members: Vetsch Susanne
Vista Study
Oct 23, 2023prospective, observational, global, multicenter study: The objective of the VISTA Study is to evaluate the safety and performance of the Navitor valve in a realworld setting. This study is intended to satisfy post-market clinical follow-up require...
Clinical Studies - Oct 23, 2023 - Oct 30, 2030
Ongoing
Project leader: Haager Philipp K.
Members: Vetsch Susanne
The Selution DeNovo Study
Sep 28, 2023A prospective, randomized, multicenter, international, open, clinical study in which the SELUTION DEB strategy was compared with the DES strategy. Study objectives: 1) At 1 year, to demonstrate non-inferiority for TVF of a treatment strategy wi...
Clinical Studies - Sep 28, 2023 - Sep 28, 2028
Ongoing
Project leader: Rigger Johannes
Members: Meier Jessica, Schneider Irene
Immunopathological pathways underlying myocarditis and inflammatory cardiomyopathy – an exploratory study
Jul 24, 2023Primary objective: Analysis of cardiac antigen- and microbiota-reactive CD4+ T cell and B cell response during development of cardiac inflammation. Secondary objectives: Analysis of clinical data, cardiac imaging and immunological parameters (HLA de...
Clinical Studies - Jul 24, 2023 - Jul 24, 2024
Ongoing
Project leader: Ludewig Burkhard
Members: Rickli Hans, Maeder Micha, Vetsch Susanne
Swiss Cardiac Amyloidosis Registry
Jul 1, 2023The aim of the Swiss-CARE registry is a comprehensive collection of clinical data and a follow-up of patients diagnosed with cardiac amyloidosis. Patients with and without therapy will be included in the registry. This will allow us to better under...
Register - Jul 1, 2023 - Jul 1, 2033
Ongoing
Project leader: Ehl Niklas
Members: Schneider Irene
Swiss Secondary Prevention and Rehabilitation Registry: SwissPR
Jul 1, 2023The rationale of this prospective longitudinal cohort study is to determine the short and long-term effects of an ambulatory cardiac rehabilitation program on key cardiovascular benchmark performance measures and its effects on major adverse cardiova...
Register - Jul 1, 2023 - Dec 31, 2040
Ongoing
Project leader: Buser Marc
Members: Schneider Irene
Oceanic AF
Jun 1, 2023A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) with apixaban for the preve...
Clinical Studies - Jun 1, 2023 - Jun 30, 2024
Completed
Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne
AmplatzerTM PFO Occluder and AmplatzerTM TalismanTM PFO Occluder PAS (“PFO PAS”) AmplatzerTM PFO Occluder and AmplatzerTM TalismanTM PFO Occluder Post Approval Study
Jun 1, 2023PFO PAS is a singel arm, multinational post-market study in patients with PFO after ischemic stroke (paradoxical embolism). Screening via PFO colloquium. Study Objectives; To demonstrate safety of the Amplatzer PFO Occluder and Amplatzer Talisman P...
Clinical Studies - Jun 1, 2023 - Jun 1, 2028
Ongoing
Project leader: Chronis Joannis
Members: Meier Jessica, Vetsch Susanne
OCEAN
May 1, 2023A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein (a).
Clinical Studies - May 1, 2023 - Dec 31, 2024
Aborted
Project leader: Bilz Stefan
Members: Räss Andrea, Rickli Hans, Vetsch Susanne
AMGEN202100057
May 1, 2022A Multicenter, Cross-sectional Study to Characterize the Distribution of Lipoprotein(a) Levels Among Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD). The purpose of the study is to characterize the distribution o...
Clinical Studies - May 1, 2022 - Mar 31, 2023
Completed
Project leader: Rickli Hans
Members: Vetsch Susanne, Bilz Stefan, Räss Andrea
MitraSwiss Register
Apr 1, 2022A longitudinal observational study of patients treated with the MitraClip system in Switzerland
Register - Apr 1, 2022 - Dec 31, 2030
Ongoing
Project leader: Haager Philipp
Members: Schneider Irene
SOS AMI Selatogrel
Jan 10, 2022Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death and treatment of acute myocardial infarction in subjec...
Clinical Studies - Jan 10, 2022 - Jan 14, 2026
Ongoing
Project leader: Maeder Micha
Members: Vetsch Susanne, Fink Karin
SeQuent® SCB "All Comers" Post Market Clinical Follow-up (PMCF)
Oct 21, 2021This study is a single armed, prospective, multi-center, observational study Planned: up to 40 study sites in the EU and selected non-EU-countries
Clinical Studies - Oct 21, 2021 - Dec 31, 2025
Ongoing
Project leader: Weilenmann Daniel
Members: Vetsch Susanne, Fink Karin
CARE-HK in HF Registry
Sep 30, 2021This study is a multinational, multicentre, non-interventional, cohort study of assessment and treatment guideline recommendations in HF patient care in a real-world setting.
Clinical Studies - Sep 30, 2021 - Dec 31, 2025
Ongoing
Project leader: Maeder Micha
Members: Vetsch Susanne, Schneider Irene
ALFA ROMEO
Jun 23, 2021Atrial fibrillation before and after patent foramen ovale closure study This is a prospective, multicenter, single-arm, observational study assessing the incidence, predictors and prognostic impact of AF occurring before (monitoring phase A) or afte...
Clinical Studies - Jun 23, 2021 - Jun 23, 2025
Ongoing
Project leader: Weilenmann Daniel
Members: Schneider Irene
SWISS-AF Control Group
Jun 17, 2021Contemporary findings from the ongoing Swiss-AF cohort study (2’415 patients with atrial fibrillation (AF) enrolled, 1’760 patients with available brain imaging) showed that patients with AF have a high burden of cerebral infarcts and other brain les...
Clinical Studies - Jun 17, 2021 - Jun 17, 2025
Ongoing
Project leader: Ammann Peter
Members: Fink Karin
CardioOnco - Diagnosing Preclinical Cardiac Dysfunction in Adult Childhood Cancer Survivors ‒ The CardioOnco study
Mar 1, 2021We aim to: 1. Assess preclinical cardiac dysfunction longitudinally using 2-dimensional (2D) and 3-dimensional (3D) conventional and 2D speckle tracking echocardiography. 2. Assess cardiopulmonary fitness using cardiopulmonary exercise testing. 3....
Clinical Studies - Mar 1, 2021 - Dec 31, 2030
Ongoing
Project leader: Scheler Eva
Members: Schneider Irene
CATCH - Cascade genetic testing of familial hypercholesterolemia: the CATCH multicenter randomized controlled trial
Dec 15, 2020To test in a multicenter open-label randomized controlled trial across Switzerland whether a cascade screening programme for FH, in comparison with usual care, will increase the detection rate of FH within families. The primary outcome will be the...
Clinical Studies - Dec 15, 2020 - Mar 31, 2024
Automatically Closed
Project leader: Rickli Hans
Members: Vetsch Susanne, Schneider Irene
SILENT 2
Dec 4, 2020Incidence of Silent Atrial Fibrillation in Patients With Clinically Silent Brain Ischemic Lesions Arterial Fibrillation (AF) is well-recognized as a cause for cryptogenic Acute Ischemic Stroke (AIS) and is associated with Silent Brain Infarction...
Clinical Studies - Dec 4, 2020 - Dec 4, 2024
Ongoing
Project leader: Ammann Peter, Kägi Georg
Members: Brenner Roman, Vetsch Susanne, Schneider Irene
SwissSCAD
Oct 1, 2020The primary aim is to gather observational data from consecutive SCAD patients in Switzerland, in order to establish a National Swiss Registry (SwissSCAD). SCAD is a poorly understood condition, affecting young patients and is associated with major...
Clinical Studies - Oct 1, 2020 - Dec 31, 2030
Ongoing
Project leader: Rickli Hans
Members: Schneider Irene