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Burkhard Ludewig

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Pikor N, Cheng H W, Onder L, Ludewig B. Development and Immunological Function of Lymph Node Stromal Cells. J Immunol 2021; 206:257-263.
   
Prados A, Onder L, Cheng H W, Mörbe U, Lütge M, Gil Cruz C, Perez Shibayama C, Koliaraki V, Ludewig B, Kollias G. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol 2021; 22:510-519.
   
ring s, krolik m, Hartmann F, Schmidt E, Ali O H, Ludewig B, Kochanek S, Flatz L. Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8 T Cell Responses. Mol Ther Oncolytics 2020; 19:179-187.
   
Bocharov G, Volpert V, Ludewig B, Meyerhans A. Editorial: Mathematical Modeling of the Immune System in Homeostasis, Infection and Disease. Front Immunol 2020; 10:2944.
   
Cosgrove J, Novkovic M, Albrecht S, Pikor N, Zhou Z, Onder L, Mörbe U, cupovic j, Miller H, Alden K, Thuery A, O'Toole P, Pinter R, Jarrett S, Taylor E, Venetz D, Heller M, Uguccioni M, Legler D F, Lacey C J, Coatesworth A, Polak W G, Cupedo T, Manoury B, Thelen M, Stein J V, Wolf M, Leake M C, Timmis J, Ludewig B, Coles M C. B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nat Commun 2020; 11:3677.
   
Guendel F, Kofoed-Branzk M, Gronke K, Tizian C, Witkowski M, Cheng H W, Heinz G A, Heinrich F, Durek P, Norris P S, Ware C F, Ruedl C, Herold S, Pfeffer K, Hehlgans T, Waisman A, Becher B, Giannou A D, Brachs S, Ebert K, Tanriver Y, Ludewig B, Mashreghi M F, Kruglov A A, Diefenbach A. Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues. Immunity 2020; 53:1015-1032.e8.
   
Novkovic M, Onder L, Bocharov G, Ludewig B. Topological Structure and Robustness of the Lymph Node Conduit System. Cell Rep 2020; 30:893-904.e6.
   
Perkey E, Maurice De Sousa D, Carrington L, Chung J, Dils A, Granadier D, Koch U, Radtke F, Ludewig B, Blazar B R, Siebel C W, Brennan T V, Nolz J, Labrecque N, Maillard I. GCNT1-Mediated -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells. J Immunol 2020; 204:1674-1688.
   
Aparicio-Domingo P, Cannelle H, Buechler M B, Nguyen S, Kallert S M, Favre S, Alouche N, Papazian N, Ludewig B, Cupedo T, Pinschewer D D, Turley S J, Luther S A. Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection. Eur J Immunol 2020;.
   
Bocharov G, Casella V, Argilaguet J, Grebennikov D, Güerri-Fernandez R, Ludewig B, Meyerhans A. Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity. Front Cell Infect Microbiol 2020; 10:559209.
   
Chauveau A, Pirgova G, Cheng H W, De Martin A, Zhou F Y, Wideman S, Rittscher J, Ludewig B, Arnon T I. Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones. Immunity 2020;.
   
Perez Shibayama C, Islander U, Lütge M, Cheng H W, Onder L, ring s, De Martin A, Novkovic M, Colston J, Gil Cruz C, Ludewig B. Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells. Sci Immunol 2020; 5:.
   
Pikor N, morbe u, Lütge M, Gil Cruz C, Perez Shibayama C, Novkovic M, Cheng H W, Nombela-Arrieta C, Nagasawa T, Linterman M A, Onder L, Ludewig B. Remodeling of light and dark zone follicular dendritic cells governs germinal center responses. Nat Immunol 2020; 21:649-659.
   
Choi S Y, Bae H, Jeong S H, Park I, Cho H, Hong S P, Lee D H, Lee C K, Park J S, Suh S H, Choi J, Yang M J, Jang J Y, Onder L, Moon J H, Jeong H S, Adams R H, Kim J M, Ludewig B, Song J H, Lim D S, Koh G Y. YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells. Nat Commun 2020; 11:519.
   
Dasoveanu D C, Park H J, Ly C L, Shipman W D, Chyou S, Kumar V, Tarlinton D, Ludewig B, Mehrara B J, Lu T T. Lymph node stromal CCL2 limits antibody responses. Sci Immunol 2020; 5:.
   
brenig r, Pop O, Triantafyllou E, Geng A, Singanayagam A, Perez Shibayama C, Besse L, cupovic j, Künzler-Heule P, Boldanova T, Brand S, Semela D, Duong F H, Weston C J, Ludewig B, Heim M H, Wendon J, Antoniades C G, bernsmeier c. Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis. Life Sci Alliance 2019; 3:.
   
Colston J M, Hutchings C, Chinnakannan S, Highton A, Perez Shibayama C, Ludewig B, Klenerman P. Divergent memory responses driven by adenoviral vectors are impacted by epitope competition. Eur J Immunol 2019;.
   
Fässler M, Diem S, Mangana J, Hasan Ali O, Berner F, Bomze D, ring s, Niederer R, Gil Cruz C, Perez Shibayama C, Krolik M, siano m, Joerger M, Recher M, Risch L, guesewell s, Risch M, Speiser D E, Ludewig B, Levesque M P, Dummer R, Flatz L. Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients. J Immunother Cancer 2019; 7:50.
   
Li C, Lam E, Perez Shibayama C, Ward L A, Zhang J, Lee D, Nguyen A, Ahmed M, Brownlie E, Korneev K V, Rojas O, Sun T, Navarre W, He H H, Liao S, Martin A, Ludewig B, Gommerman J L. Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity. Sci Immunol 2019; 4:.
   
Zarak-Crnkovic M, Kania G, Jaźwa-Kusior A, Czepiel M, Wijnen W J, Czyż J, Müller-Edenborn B, Vdovenko D, Lindner D, Gil Cruz C, Bachmann M, Westermann D, Ludewig B, Distler O, Lüscher T F, Klingel K, Eriksson U, Błyszczuk P. Heart non-specific effector CD4 T cells protect from postinflammatory fibrosis and cardiac dysfunction in experimental autoimmune myocarditis. Basic Res Cardiol 2019; 115:6.
   
Camara A, Cordeiro O G, Alloush F, Sponsel J, Chypre M, Onder L, Asano K, Tanaka M, Yagita H, Ludewig B, Flacher V, Mueller C G. Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche. Immunity 2019; 50:1467-1481.e6.
   
Dubey L K, Ludewig B, Luther S A, Harris N L. IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells. Cell Rep 2019; 27:2442-2458.e5.
   
Perez Shibayama C, Gil Cruz C, Ludewig B. Fibroblastic reticular cells at the nexus of innate and adaptive immune responses. Immunol Rev 2019; 289:31-41.
   
Solmaz G, Puttur F, Francozo M, Lindenberg M, Guderian M, Swallow M, Duhan V, Khairnar V, Kalinke U, Ludewig B, Clausen B E, Wagner H, Lang K S, Sparwasser T D. TLR7 Controls VSV Replication in CD169 SCS Macrophages and Associated Viral Neuroinvasion. Front Immunol 2019; 10:466.
   
Rieckmann M, Delgobo M, Gaal C, Büchner L, Steinau P, Reshef D, Gil Cruz C, Ter Horst E N, Kircher M, Reiter T, Heinze K G, Niessen H W, Krijnen P A, van der Laan A M, Piek J J, Koch C, Wester H J, Lapa C, Bauer W R, Ludewig B, Friedman N, Frantz S, Hofmann U, Ramos G C. Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses. J Clin Invest 2019; 130:.
   
Ludewig B. Rolf Zinkernagel and the co-discovery of MHC restriction together with Peter Doherty. Allergy 2019;.
   
Argilaguet J, Pedragosa M, Esteve-Codina A, Riera G, Vidal E, Gil Cruz C, Casella V, Andreu D, Kaisho T, Bocharov G, Ludewig B, Heath S, Meyerhans A. Systems analysis reveals complex biological processes during virus infection fate decisions. Genome Res 2019; 29:907-919.
   
Cheng H W, Onder L, Novkovic M, Soneson C, Lütge M, Pikor N, Scandella E, Robinson M D, Miyazaki J I, Tersteegen A, Sorg U, Pfeffer K, Rülicke T, Hehlgans T, Ludewig B. Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun 2019; 10:1739.
   
Denton A E, Innocentin S, Carr E J, Bradford B M, Lafouresse F, Mabbott N A, Mörbe U, Ludewig B, Groom J R, Good-Jacobson K L, Linterman M A. Type I interferon induces CXCL13 to support ectopic germinal center formation. J Exp Med 2019;.
   
Gil Cruz C, Perez Shibayama C, De Martin A, Ronchi F, van der Borght K, Niederer R, Onder L, Lütge M, Novkovic M, Nindl V, Ramos G, Arnoldini M, Slack E M C, Boivin-Jahns V, Jahns R, Wyss M, Mooser C, Lambrecht B N, Maeder M T, Rickli H, Flatz L, Eriksson U, Geuking M B, McCoy K D, Ludewig B. Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy. Science 2019; 366:881-886.
   
Lercher A, Bhattacharya A, Popa A M, Caldera M, Schlapansky M F, Baazim H, Agerer B, Gürtl B, Kosack L, Májek P, Brunner J S, Vitko D, Pinter T, Genger J W, Orlova A, Pikor N, Reil D, Ozsvár-Kozma M, Kalinke U, Ludewig B, Moriggl R, Bennett K L, Menche J, Cheng P N, Schabbauer G, Trauner M, Klavins K, Bergthaler A. Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function. Immunity 2019; 51:1074-1087.e9.
   
Takeuchi A, Ozawa M, Kanda Y, Kozai M, Ohigashi I, Kurosawa Y, Rahman M A, Kawamura T, Shichida Y, Umemoto E, Miyasaka M, Ludewig B, Takahama Y, Nagasawa T, Katakai T. A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node. Front Immunol 2018; 9:2196.
   
Cheng H W, Onder L, cupovic j, Bösch M, Novkovic M, Pikor N, Tarantino I, Rodriguez R, Schneider T, Jochum W, Brutsche M, Ludewig B. CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses. J Allergy Clin Immunol 2018;.
   
Onder L, Ludewig B. A Fresh View on Lymph Node Organogenesis. Trends Immunol 2018; 39:775-787.
   
Perez Shibayama C, Gil Cruz C, Cheng H W, Onder L, Printz A, morbe u, Novkovic M, Li C, Lopez-Macias C, Buechler M B, Turley S J, Mack M, Soneson C, Robinson M D, Scandella E, Gommerman J, Ludewig B. Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity. Sci Immunol 2018; 3:.
   
Novkovic M, Onder L, Cheng H W, Bocharov G, Ludewig B. Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape. Front Immunol 2018; 9:2428.
   
Baumann N S, Torti N, Welten S P M, Barnstorf I, Borsa M, Pallmer K, Oduro J D, Cicin-Sain L, Ikuta K, Ludewig B, Oxenius A. Tissue maintenance of CMV-specific inflationary memory T cells by IL-15. PLoS Pathog 2018; 14:e1006993.
   
Bogdanova D, Takeuchi A, Ozawa M, Kanda Y, Rahman M A, Ludewig B, Kinashi T, Katakai T. Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs. J Immunol 2018; 201:3580-3586.
   
Van der Borght K, Scott C L, Martens L, Sichien D, Van Isterdael G, Nindl V, Saeys Y, Boon L, Ludewig B, Gillebert T C, Lambrecht B N. Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells. Front Immunol 2018; 9:2714.
   
Onder L, Ludewig B. Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius. Trends Immunol 2018; 39:952-953.
   
Emgård J, Kammoun H, García-Cassani B, Chesné J, Parigi S M, Jacob J M, Cheng H W, Evren E, Das S, Czarnewski P, Sleiers N, Melo-Gonzalez F, Kvedaraite E, Svensson M, Scandella E, Hepworth M R, Huber S, Ludewig B, Peduto L, Villablanca E J, Veiga-Fernandes H, Pereira J P, Flavell R A, Willinger T. Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation. Immunity 2018; 48:120-132.e8.
   
Bösch M, Onder L, Cheng H W, Novkovic M, morbe u, Sopper S, Gastl G, Jochum W, ruhstaller t, knauer m, Ludewig B. Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness. Oncoimmunology 2018; 7:e1414129.
   
Cossarizza A, Chang H D, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer W M, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais P E, Brinkman R R, Büscher M, Busch D H, Bushnell T P, Cao X, Cavani A, Chattopadhyay P K, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang V D, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg V S, Dörner T, Ehrhardt G R A, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Falk C S, Fehniger T A, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds G A, Frenette P S, Galbraith D, Garbi N, García-Godoy M D, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear C S, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser A E, Haviland D L, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston J P, Hoyer B F, Huang B, Hunter C A, Iannone A, Jäck H M, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold M D, Levings M K, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker H T, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei H E, Melchers F, Melzer S, Mielenz D, Mills K, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann T R, Müller S, Müller W, Münz C, Multhoff G, Munoz L E, Murphy K M, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O'Connor J E, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley A G, Podolska M J, Pucillo C, Quataert S A, Radstake T R D J, Rajwa B, Rebhahn J A, Recktenwald D, Remmerswaal E B M, Rezvani K, Rico L G, Robinson J P, Romagnani C, Rubartelli A, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid S A, Schmitt S, Schober K, Schüler T, Schulz A R, Schumacher T, Scotta C, Shankey T V, Shemer A, Simon A K, Spidlen J, Stall A M, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier R A W, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk H D, von Volkmann K, Waisman A, Walker R, Ward M D, Warnatz K, Warth S, Watson J V, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J. Guidelines for the use of flow cytometry and cell sorting in immunological studies. Eur J Immunol 2017; 47:1584-1797.
   
Chung J, Ebens C L, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran I T, Chai Q, Onder L, Yan M, Reddy P, Blazar B R, Huang A Y, Brennan T V, Bishop D K, Ludewig B, Siebel C W, Radtke F, Luther S A, Maillard I. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest 2017; 127:1574-1588.
   
Carreño J M, Perez Shibayama C, Gil Cruz C, López-Macías C, vernazza p, Ludewig B, albrich w. Evolution of Salmonella Typhi outer membrane protein-specific T and B cell responses in humans following oral Ty21a vaccination: A randomized clinical trial. PLoS ONE 2017; 12:e0178669.
   
Novkovic M, Onder L, Bocharov G, Ludewig B. Graph Theory-Based Analysis of the Lymph Node Fibroblastic Reticular Cell Network. Methods Mol Biol 2017; 1591:43-57.
   
Kindler E, Gil Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw H H, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld F J M, Silverman R H, Keller M, Ludewig B, Bergmann C C, Ziebuhr J, Weiss S R, Kalinke U, Thiel V. Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS Pathog 2017; 13:e1006195.
   
Dubey L K, Karempudi P, Luther S A, Ludewig B, Harris N L. Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis. Nat Commun 2017; 8:367.
   
Van der Borght K, Scott C L, Nindl V, Bouché A, Martens L, Sichien D, Van Moorleghem J, Vanheerswynghels M, De Prijck S, Saeys Y, Ludewig B, Gillebert T, Guilliams M, Carmeliet P, Lambrecht B N. Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells. Cell Rep 2017; 18:3005-3017.
   
Onder L, morbe u, Pikor N, Novkovic M, Cheng H W, Hehlgans T, Pfeffer K, Becher B, Waisman A, Rülicke T, Gommerman J, Mueller C G, Sawa S, Scandella E, Ludewig B. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity 2017; 47:80-92.e4.
   
Pikor N, cupovic j, Onder L, Gommerman J L, Ludewig B. Stromal Cell Niches in the Inflamed Central Nervous System. J Immunol 2017; 198:1775-1781.
   
cupovic j, Onder L, Gil Cruz C, Weiler E, Caviezel-Firner S, Perez Shibayama C, Rülicke T, Bechmann I, Ludewig B. Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation. Immunity 2016; 44:622-33.
   
Takeda A, Kobayashi D, Aoi K, Sasaki N, Sugiura Y, Igarashi H, Tohya K, Inoue A, Hata E, Akahoshi N, Hayasaka H, Kikuta J, Scandella E, Ludewig B, Ishii S, Aoki J, Suematsu M, Ishii M, Takeda K, Jalkanen S, Miyasaka M, Umemoto E. Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility. Elife 2016; 5:.
   
Gil Cruz C, Perez Shibayama C, Onder L, chai q, cupovic j, Cheng H W, Novkovic M, Lang P A, Geuking M B, McCoy K D, Abe S, Cui G, Ikuta K, Scandella E, Ludewig B. Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs. Nat Immunol 2016; 17:1388-1396.
   
Bösch M, Sopper S, Zeimet A G, Reimer D, Gastl G, Ludewig B, Wolf D. Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche. Biochim Biophys Acta 2016; 1866:276-289.
   
Cordeiro O G, Chypre M, Brouard N, Rauber S, Alloush F, Romera-Hernandez M, Bénézech C, Li Z, Eckly A, Coles M C, Rot A, Yagita H, Léon C, Ludewig B, Cupedo T, Lanza F, Mueller C G. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS ONE 2016; 11:e0151848.
   
Dubey L K, Lebon L, Mosconi I, Yang C Y, Scandella E, Ludewig B, Luther S A, Harris N L. Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection. Cell Rep 2016; 15:1527-41.
   
Carreño J M, Perez Shibayama C, Gil Cruz C, printz a, Pastelin R, Isibasi A, Chariatte D, Tanoue Y, López-Macías C, Gander B, Ludewig B. PLGA-microencapsulation protects Salmonella typhi outer membrane proteins from acidic degradation and increases their mucosal immunogenicity. Vaccine 2016; 34:4263-9.
   
Novkovic M, Onder L, cupovic j, Abe J, Bomze D, Cremasco V, Scandella E, Stein J V, Bocharov G, Turley S J, Ludewig B. Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality. PLoS Biol 2016; 14:e1002515.
   
Onder L, Nindl V, Scandella E, chai q, Cheng H W, Caviezel-Firner S, Novkovic M, Bomze D, Maier R, Mair F, Ledermann B, Becher B, Waisman A, Ludewig B. Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction. Eur J Immunol 2015;.
   
Onder L, Ludewig B. Another TLO in the Wall: Education and Control of T Cells in Atherosclerotic Arteries. Immunity 2015; 42:981-3.
   
Rodda L B, Bannard O, Ludewig B, Nagasawa T, Cyster J G. Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells. J Immunol 2015; 195:4781-91.
   
Mair F, Joller S, Hoeppli R, Onder L, Hahn M, Ludewig B, Waisman A, Becher B. The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells. Elife 2015; 4:.
   
Perez Shibayama C, Ludewig B. Tuning up FALCs: immunological shielding in the body cavities. Nat Immunol 2015; 16:796-8.
   
Bhattacharya A, Hegazy A N, Deigendesch N, Kosack L, cupovic j, Kandasamy R K, Hildebrandt A, Merkler D, Kühl A A, Vilagos B, Schliehe C, Panse I, Khamina K, Baazim H, Arnold I, Flatz L, Xu H C, Lang P A, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Bergthaler A. Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity 2015; 43:974-86.
   
Cremasco V, Woodruff M C, Onder L, Cupovic J, Nieves-Bonilla J M, Schildberg F A, Chang J, Cremasco F, Harvey C J, Wucherpfennig K, Ludewig B, Carroll M C, Turley S J. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat Immunol 2014; 15:973-81.
   
Tschismarov R, Firner S, Gil Cruz C, Göschl L, Boucheron N, Steiner G, Matthias P, Seiser C, Ludewig B, Ellmeier W. HDAC1 controls CD8+ T cell homeostasis and antiviral response. PLoS ONE 2014; 9:e110576.
   
Sage A P, Murphy D, Maffia P, Masters L M, Sabir S R, Baker L L, Cambrook H, Finigan A J, Ait-Oufella H, Grassia G, Harrison J E, Ludewig B, Reith W, Hansson G K, Reizis B, Hugues S, Mallat Z. MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity. Circulation 2014; 130:1363-73.
   
Perez Shibayama C, Gil Cruz C, Pastelin-Palacios R, Cervantes-Barragan L, Hisaki E, chai q, Onder L, Scandella E, Regen T, Waisman A, Isibasi A, López-Macías C, Ludewig B. IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi. J Immunol 2014; 192:5192-200.
   
Perez Shibayama C, Gil Cruz C, Ludewig B. Plasticity and complexity of B cell responses against persisting pathogens. Immunol Lett 2014; 162:53-8.
   
Moalli F, cupovic j, Thelen F, Halbherr P, Fukui Y, Narumiya S, Ludewig B, Stein J V. Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions. J Exp Med 2014; 211:2507-17.
   
Fasnacht N, Huang H Y, Koch U, Favre S, Auderset F, chai q, Onder L, Kallert S, Pinschewer D D, MacDonald H R, Tacchini-Cottier F, Ludewig B, Luther S A, Radtke F. Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med 2014; 211:2265-79.
   
Astarita J L, Cremasco V, Fu J, Darnell M C, Peck J R, Nieves-Bonilla J M, Song K, Kondo Y, Woodruff M C, Gogineni A, Onder L, Ludewig B, Weimer R M, Carroll M C, Mooney D J, Xia L, Turley S J. The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture. Nat Immunol 2014; 16:75-84.
   
Bocharov G, Luzyanina T, cupovic j, Ludewig B. Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis. Front Immunol 2013; 4:264.
   
Bolinger B, Sims S, O'Hara G, de Lara C, Tchilian E, Firner S, Engeler D S, Ludewig B, Klenerman P. A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector. J Immunol 2013; 190:4162-74.
   
mueller r, Maier R, Hoschler K, Zambon M, Ludewig B, Herrmann M, Schulze-Koops H, von Kempis J. Efficient boosting of the antiviral T cell response in B cell-depleted patients with autoimmune rheumatic diseases following influenza vaccination. Clin Exp Rheumatol 2013; 31:723-30.
   
Onder L, Danuser R, Scandella E, Firner S, chai q, Hehlgans T, Stein J V, Ludewig B. Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation. J Exp Med 2013; 210:465-73.
   
Perez Shibayama C, Gil Cruz C, Nussbacher M, Allgäuer E, Cervantes-Barragan L, Züst R, Ludewig B. Dendritic cell-specific delivery of Flt3L by coronavirus vectors secures induction of therapeutic antitumor immunity. PLoS ONE 2013; 8:e81442.
   
Luzyanina T, cupovic j, Ludewig B, Bocharov G. Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division. J Math Biol 2013;.
   
Iolyeva M, Aebischer D, Proulx S T, Willrodt A H, Ecoiffier T, Häner S, Bouchaud G, Krieg C, Onder L, Ludewig B, Santambrogio L, Boyman O, Chen L, Finke D, Halin C. Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage. Blood 2013; 122:2271-81.
   
Caviezel-Firner S, Engeler D S, Bolinger B, Onder L, Scandella E, Yu M, Kroczek R A, Ludewig B. Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell-mediated vascular immunopathology. Eur J Immunol 2013; 43:3233-43.
   
chai q, Onder L, Scandella E, Gil Cruz C, Perez Shibayama C, cupovic j, Danuser R, Sparwasser T, Luther S A, thiel v, Rülicke T, Stein J V, Hehlgans T, Ludewig B. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity 2013; 38:1013-24.
   
Coelho F M, Natale D, Soriano S F, Hons M, Swoger J, Mayer J, Danuser R, Scandella E, Pieczyk M, Zerwes H G, Junt T, Sailer A W, Ludewig B, Sharpe J, Figge M T, Stein J V. Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions. Blood 2013; 121:4101-9.
   
Ludewig B, Stein J V, Sharpe J, cervantes l, thiel v, Bocharov G. A global "imaging'' view on systems approaches in immunology. Eur J Immunol 2012; 42:3116-25.
   
Engeler D S, Scandella E, Ludewig B, Schmid H P. Ciprofloxacin and epirubicin synergistically induce apoptosis in human urothelial cancer cell lines. Urol Int 2012; 88:343-9.
   
nindl v, Maier R, Ratering D, degiuli r, Züst R, thiel v, Scandella E, Di Padova F, Kopf M, Rudin M, Rülicke T, Ludewig B. Cooperation of Th1 and Th17 cells determines transition from autoimmune myocarditis to dilated cardiomyopathy. Eur J Immunol 2012; 42:2311-21.
   
Onder L, Narang P, Scandella E, chai q, Iolyeva M, Hoorweg K, Halin C, Richie E, Kaye P, Westermann J, Cupedo T, Coles M, Ludewig B. IL-7-producing stromal cells are critical for lymph node remodeling. Blood 2012; 120:4675-83.
   
Weber S S, Joller N, Küntzel A B, Spörri R, Tchang V S, Scandella E, Rösli C, Ludewig B, Hilbi H, Oxenius A. Identification of protective B cell antigens of Legionella pneumophila. J Immunol 2012; 189:841-9.
   
Cervantes-Barragan L, Bechmann I, Waisman A, Lahl K, Sparwasser T, thiel v, Ludewig B. Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection. J Immunol 2012; 188:3678-85.
   
Frebel H, nindl v, Schuepbach R A, Braunschweiler T, Richter K, Vogel J, Wagner C A, Loffing-Cueni D, Kurrer M, Ludewig B, Oxenius A. Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice. J Exp Med 2012; 209:2485-99.
   
cervantes l, Lewis K L, thiel v, Hugues S, Reith W, Ludewig B, Reizis B. Plasmacytoid dendritic cells control T-cell response to chronic viral infection. Proc Natl Acad Sci USA 2012; 109:3012-7.
   
Onder L, nindl v, Ludewig B. Tight control - decision-making during T cell-vascular endothelial cell interaction. Front Immunol 2012; 3:279.
   
Gil Cruz C, Perez Shibayama C, Waisman A, Bechmann I, thiel v, cervantes l, Ludewig B. T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease. Proc Natl Acad Sci USA 2012; 109:1233-8.
   
Onder L, Scandella E, chai q, Mayer C T, Sparwasser T, thiel v, Rülicke T, Ludewig B. A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo. Front Immunol 2011; 2:50.
   
zuest r, cervantes l, habjan m, Maier R, Neuman B W, Ziebuhr J, Szretter K J, Baker S C, Barchet W, Diamond M S, Siddell S G, Ludewig B, thiel v. Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol 2011; 12:137-43.
   
Pastelin-Palacios R, Gil Cruz C, Perez Shibayama C, Moreno-Eutimio M A, cervantes l, Arriaga-Pizano L, Ludewig B, Cunningham A F, García-Zepeda E A, Becker I, Alpuche-Aranda C, Bonifaz L, Gunn J S, Isibasi A, López-Macías C. Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium. Immunology 2011; 133:469-81.
   
Ludewig B, cervantes l. CD169(+) macrophages take the bullet. Nat Immunol 2011; 13:13-4.
   
Bocharov G A, Danilov A A, Vassilevski Y V, Marchuk G I, Chereshnev V A, Ludewig B. Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration. Dokl Biol Sci 2011; 439:194-6.
   
Lang P A, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, cervantes l, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, Häussinger D, Ohashi P S, Zinkernagel R M, Lang K S. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology 2010; 52:25-32.
   
Schwendener R A, Ludewig B, Cerny A, Engler O. Liposome-based vaccines. Methods in molecular biology (Clifton, N.J.) 2010; 605:163-75.
   
 
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