Kantonsspital St.Gallen

[Heart failure with preserved ejection fraction (HFpEF)]

Micha T. Maeder, Marc Buser, Roman Brenner & Hans Rickli

abstract Heart failure with preserved ejection fraction (HFpEF) Abstract. Heart failure with preserved left ventricular ejection fraction (HFpEF) is a very common form of heart failure typically seen in older patients and associated with poor prognosis. Patients with HFpEF are characterized by a s small left ventricle with concentric remodeling and abnormal compliance, which under the impact of additional cardiovascular mechanisms and non-cardiac comorbidities, leads to the cardinal symptoms of dyspnea and exercise intolerance. The diagnosis of HFpEF is still under debate, and the therapeutic options are limited despite intensive research efforts. In the present review article, we provide an overview of the current understanding of the pathiohysiology of HFpEF, the current diagnostic approach, and a summary of the available evidence on treatment.
citation Maeder M T, Buser M, Brenner R, Rickli H. [Heart failure with preserved ejection fraction (HFpEF)]. Ther Umsch 2018; 75:161-169.
type journal paper/review (Translation2::getLang(): unknown language "". Use Translation2::setLang() to set a default language.)
date of publishing 9-2018
journal title Ther Umsch (75/3)
ISSN print 0040-5930
pages 161-169
PubMed 30145974
DOI 10.1024/0040-5930/a000983