The role of neoadjuvant chemotherapy and interval laparotomy in advanced ovarian cancer

Publikation

The role of neoadjuvant chemotherapy and interval laparotomy in advanced ovarian cancer

Wissenschaftlicher Artikel/Review - 01.03.2002

Huober Jens, Meyer A, Wagner U, Wallwiener D

Zitation

Huober J, Meyer A, Wagner U, Wallwiener D. The role of neoadjuvant chemotherapy and interval laparotomy in advanced ovarian cancer. Journal of cancer research and clinical oncology 2002; 128:153-60.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Journal of cancer research and clinical oncology 2002; 128

Veröffentlichungsdatum

01.03.2002

ISSN (Druck)

0171-5216

Seiten

153-60

Kurzbeschreibung/Zielsetzung

Radical debulking surgery allows for optimal cytoreduction in less than 50% of patients with advanced ovarian cancer. In spite of highly efficient chemotherapeutic regimens, the prognosis of patients with residual tumor masses larger than 1 cm in diameter following staging laparotomy is very poor. This observation led to the initiation of numerous trials evaluating the feasibility and efficiency of the use of primary chemotherapy followed by interval laparotomy in women with advanced ovarian cancer. The available data is presented and discussed in this review.