Projects

Eine Verlängerungsstudie zur Beurteilung von Langzeitsicherheit, Verträglichkeit, Pharmakokinetik und Wirkung auf das Fortschreiten der Erkrankung von BIIB078 bei zuvor behandelten Erwachsenen mit C9ORF72-assoziierter amyotropher Lateralsklerose

Clinical Studies - Sep 1, 2020 - Dec 31, 2024

Completed

Project leader: Weber Markus

a phase 3, double-blind, multicenter study of evaluate the long-term safety and efficacy of baricitinib in patients with SLE.

Clinical Studies - Aug 12, 2020 - Aug 12, 2022

Completed

Project leader: Rubbert-Roth Andrea
Members: Peischl Riana, Bartz-Batliner Mira

Treatment patterns and Outcomes across the disease Continuum in patients with CAD and/or PAD The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or sym...

Clinical Studies - Jul 14, 2020 - Apr 14, 2023

Completed

Project leader: Rickli Hans
Members: Fink Karin

Post-market registry to evaluate the safety and efficacy of the Supraflex Cruz™ sirolimus-eluting coronary stent system in the treatment of all-comer patients with coronary artery disease

Clinical Studies - Jul 13, 2020 - Dec 31, 2022

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene, Fink Karin

MVX-ONCO-1 is a form of active specific immunotherapy, a process by which the patient’s immune response to tumor cells is stimulated and/or augmented. MVX-ONCO-1 is a patient specific, cell-based, immunotherapy composed of: a. An immune-modulator (...

Clinical Studies - Jul 10, 2020 - Nov 8, 2023

Completed

Project leader: Rordorf Tamara

Mit der vorliegenden Studie sollen Daten von Patienten, die eine Therapie im ZIM in Anspruch genommen haben, nach demografischen und krankheits-spezifischen Charakteristika ausgewertet werden. Dies ermöglicht die Anpassung des bestehenden Angebotes a...

Clinical Studies - Jul 7, 2020 - Jul 7, 2021

Completed

Project leader: Schlaeppi Marc, Templeton Arnoud
Members: Schlegel Tiffany

Traumatisierungen sind klinisch hoch relevant, gerade auch in den medizinisch-somatischen Fachgebieten. Trotz Fortschritten in den letzten Jahrzehnten ist deren klinische Versorgung noch unzureichend – mit ungünstigen gesundheitlichen Auswirkungen fü...

Clinical Studies - Jul 1, 2020 - Dec 31, 2021

Completed

Project leader: Schmid Dagmar
Members: Hornung René, Schmidt Roger, Krolak Monika, Nobel Gloria, Germann Nicolas, Schönenberger Michelle, Hämmerli Keller Katja

Health consequences of the Burden of atrial fibrillation The added information of measuring AF burden and measuring cardiac dimensions and function in an AF patient population where brain MRIs are available, could provide further evidence toward...

Clinical Studies - Apr 6, 2020 - Apr 6, 2024

Completed

Project leader: Ammann Peter
Members: Altmann David, Fink Karin

This study is a post-market clinical follow-up (PMCF) study to identify and evaluate residual risks associated with the use of the BIOMONITOR III that are discovered or remain even after risk analysis, risk mitigation and successful conformity assess...

Clinical Studies - Feb 10, 2020 - Jan 21, 2022

Completed

Project leader: Ammann Peter
Members: Schneider Irene

Multicenter, randomized, active comparator-controlled, double-blind, double-dummy, parallel group, dose-finding Phase 2 study to compare the safety of the oral FXIa inhibitor BAY 2433334 to apixaban in patients with atrial fibrillation Primary Safet...

Clinical Studies - Jan 21, 2020 - Dec 7, 2021

Completed

Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne

The aim of this study is to elucidate a novel biomarker constellation with superior predictive value for PD-1/PD-L1-targeted immunotherapy in advanced non-small cell lung cancer.

Fundamental Research - Jan 1, 2020 - Dec 31, 2021

Completed

Project leader: Bösch Maximilian
Members: Baty Florent, Brutsche Martin, Früh Martin, Jörger Markus

The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or symptomatic peripheral artery disease (PAD) treated with rivaroxaban 2.5 mg[BID] for the prevention of...

Clinical Studies - Nov 19, 2019 - Dec 21, 2021

Completed

Project leader: Rickli Hans
Members: Fink Karin

Netzwerke sind modern und gelten auch als Hoffnungsträger für die fachärztliche Weiterbildung. Inwieweit vermeintliche Vorteile vom ärztlichen Nachwuchs tatsächlich als solche wahrgenommen werden, ist jedoch unklar. Das Forschungsprojekt sollte kläre...

Healthcare Research - Nov 1, 2019 - Jan 31, 2022

Completed

Project leader: Thanner Mirjam
Members: Winder Franziska, Schlegel A, Von Szadkowski C, Hornung René

Die jährliche Impfung ist die vorrangige Strategie zur Grippevorbeugung und wird für Transplantationspatienten dringend empfohlen. Leider ist die Wirksamkeit des Standardimpfstoffes bei Patienten, welche eine Organtransplantation hatten, im Vergleich...

Clinical Studies - Oct 1, 2019 - Jul 1, 2020

Completed

Project leader: Binet Françoise-Isabelle

A Randomized, Controlled Phase 3 Study of Cabozantinib (XL184) in Combination with Atezolizumab versus Sorafenib in Subjects with Advanced Hepatocellular Carcinoma Who Have Not Received Previous Systemic Anticancer Therapy Randomisation 2:1:1:1 Cabo...

Clinical Studies - Sep 1, 2019 - Nov 28, 2020

Completed

Project leader: Semela David
Members: Stillhard Roman

A PHASE 4, MULTICENTER, SINGLE-ARM, OPENLABEL STUDY TO EVALUATE THE IMPACT OF APREMILAST (CC-10004) ON MRI OUTCOMES IN SUBJECTS WITH PSORIATIC ARTHRITIS

Clinical Studies - Jul 31, 2019 - Aug 31, 2021

Completed

Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Neumann Thomas, Sasselli Clelia, Peischl Riana

Prospektive nicht-interventionelle Studie zur optimierten Behandlung einer therapierefraktären Hypercholesterinämie bei Patienten mit heterozygoter familiärer Hypercholesterinämie oder klinisch manifester atherosklerotischer kardiovaskulärer Erkranku...

Clinical Studies - Apr 8, 2019 - Jan 15, 2021

Completed

Project leader: Rickli Hans
Members: Gemperle Michaela

This CE Mark study is a prospective, multi-center, single-arm investigational study to support commercialization of the FlexNav™ Delivery System and Loading System in Europe. The design of this clinical investigation is in compliance to ISO standards...

Clinical Studies - Mar 22, 2019 - Mar 30, 2021

Completed

Project leader: Haager Philipp
Members: Vetsch Susanne

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study of Baricitinib in Patients with systemic lupus erythematosus (SLE).

Clinical Studies - Feb 28, 2019 - Feb 28, 2022

Completed

Project leader: Rubbert-Roth Andrea
Members: Neumann Thomas, Bartz-Batliner Mira, Hutz Carina Liane, Peischl Riana, Sasselli Clelia

Ziele: Aus den klinischen Daten (Anamnese, körperliche Untersuchung und einem der Ischämietests [Ergometrie, Stress-Echo, Stress MRI) wird mit einer logistischen Regression eine Wahrscheinlichkeits-funktion abgeleitet. Als Referenzuntersuchung gelten...

Clinical Studies - Feb 1, 2019 - Mar 31, 2022

Completed

Project leader: Rickli Hans
Members: Schneider Irene