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EORTC 1702-LCG-ROG Targeted therapy with or without dose-intensified radiotterapy in oligo-progressive disease (OPD) in oncogene Addicted Lung Tumors

Markus Glatzer

Kurzfassung

Targeted therapy beyond Progression with or without dose-intensified radiotHerapy in oligo-progressive disease (OPD) in oncogene Addicted Lung Tumors (HALT)

Objectives: To determine wether in patients with Mutation positive advanced NSCLC the use of SBRT to ≤ 3 sites of OPD with continuation of TKI improves Progression free survival (PFS) compared with continuation of TKI alone.

Target: 110 Patients for Phase II component
   
Art des Forschungsprojektes Klinische Forschung
Status Geplant
Projektstart 2019
Projektende 2025
Studiendesign Multicenter, Randomized Phase II / III Trial
Verantwortliche Person / Hauptpr├╝farzt am KSSG Dr. Markus Glatzer