Kantonsspital St.Gallen

SAKK 66/18: A phase Ib trial of copanlisib in combina-tion with venetoclax in patients with relapsed or refrac-tory lymphoma

Dagmar Hess

abstract A significant number of patients with non-Hodgkin lym-phoma (NHL) are not cured with available treatments and will eventually relapse. Those patients might not be able to tolerate more bone marrow toxicity, limiting their treatment options. Preclinical in vitro studies have demonstrated a synergism of venetoclax and copanlisib in different lym-phomas. This may represent a safe and effective therapy for patients who relapsed or did not respond to standard therapy.
type of project clinical studies
status scheduled
start of project 2019
end of project 2022
study design Phase I
responsible person Dagmar Hess