Kantonsspital St.Gallen
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Aktuell veröffentlichte Forschungsprojekte
MK-7902-005 A Multicenter, Open-label Phase 2 Study of...
2021-05-07
The rationale for this study comes from preclinical models, in which lenvatinib decreased the tumor-associated macrophage (TAM) population, which is known as an immune-regulator in the tumor microenvironment. The decrease in TAM population was accompanied by an increase in activated cytotoxic T-cell populations through stimulation of ...
Bayer 20324
2021-04-21
TRK fusion cancer is rare but presents as a variety of solid tumors. Larotrectinib is a highly selective TRK inhibitor that, in a pooled analysis of patients in phase 1/2 clinical trials, demonstrated an effective and sustained response in the majority of patients with TRK fusion cancer. Because of the limited number of patients treated ...
A multicenter, non-randomized, open-label phase 1b study...
2021-04-21
BAY-1895344 und Pembrolizumab bei ausgewählten Tumoren mit genetischen Alterationen von ATM.
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