Unit
Department of Radiation Oncology
RO · Dept. IV
ScintiPOF: development of scintillation materials based on perovskitepolymer optical fiber composites for high-precision radiation oncology
Apr 3, 2023Radiation Oncology today is more targeted, personalized, and deals with much smaller treatment regions. The small and highly sophisticated dose distributions pose great challenges for modern radiation dosimetry. High performance detectors are used to...
Fundamental Research - Apr 3, 2023 - Mar 28, 2025
Ongoing
Project leader: Buchauer Konrad
Application of an IT knowledge base to improve decision-making for breast cancer in radiation oncology
Mar 7, 2023
Clinical Studies - Mar 7, 2023 - Sep 30, 2024
Ongoing
Project leader: Dennstädt Fabio, Zink Johannes
Members: Putora Paul Martin, Glatzer Markus, Plasswilm Ludwig
Personalisierung der Blasenkrebstherapie anhand von Unterschieden im Mikrobiom der Blase und von Stuhlproben
Feb 15, 2023Towards individualization of bladder cancer therapy: the role of microbiome in BCG responsiveness prediction
Clinical Studies - Feb 15, 2023 - Oct 15, 2024
Ongoing
Project leader: Engeler Daniel
Members: Langenauer Janine, Lyatoshinsky Pavel, Patzl Sigrid, Zürn Karin
EORTC 1901-LCG PRIMALung Study
Jan 3, 2022PRophylactic cerebral Irradiation or active MAgnetic resonance imaging surveillance in small-cell Lung cancer patients (PRIMALung study)
Clinical Studies - Jan 3, 2022 - Nov 3, 2030
Scheduled
Project leader: Putora Paul Martin
Members: Glatzer Markus, Dennstädt Fabio
Role of Brachytherapy in the post-operative management of endometrial cancer: decision-making analysis among European experts“
Feb 4, 2021To better understand decision-making processes for postoperative brachytherapy in endometrial cancer we want to initiate a project using an approach developed in our institution (objective consensus methodology) among European experts for this indica...
Clinical Studies - Feb 4, 2021 - Oct 31, 2021
Automatically Closed
Project leader: Glatzer Markus
Decision-Making Analysis of next generation sequencing in glioblastoma in Switzerland
Jan 1, 2021Glioblastoma is the most frequent and most malignant primary brain tumour with an annual incidence of 3.2/100’000 1,2. The combination of histopathological features (nuclear atypia, mitosis, neoangiogenesis and/or necrosis) and molecular aberrations...
Clinical Studies - Jan 1, 2021 - Dec 1, 2021
Automatically Closed
Members: Putora Paul Martin
Checkmate 73L (CA20973L)
Jan 1, 2020A Phase 3, Randomized, Open Label Study to Compare Nivolumab plus Concurrent Chemoradiotherapy (CCRT) followed by Nivolumab plus Ipilimumab or Nivolumab plus CCRT Followed by Nivolumab vs CCRT followed by Durvalumab in Previously Untreated, Locally A...
Clinical Studies - Jan 1, 2020 - Dec 11, 2023
Automatically Closed
Members: Glatzer Markus
SAKK 01/18 Reduced intensity radio-chemotherapy for satge IIA/B seminoma. A multicenter, open label phase II trial with 2 cohorts
Jul 24, 2019Main objective: To investigate efficacy of a stage-adapted tratment regimen in stage IIA/B seminoma based on the preliminary experience gained in SAKK 01/10. The Goal is to further safely de-escalate Treatment while maintaining / enhancing efficacy.
Clinical Studies - Jul 24, 2019 - Jul 24, 2030
Ongoing
Project leader: Putora Paul Martin
Members: Plasswilm Ludwig, Rothermundt Christian, Patzl Sigrid, Fischer Stefanie
DOSIS RCT_Dose-intensified-Image-guided Fractionatet Stereotactic Body Radiation Therapy for Painful Spinal Metastasis versus Conventional Therapy: A Randomized Controlled Trial
Jul 3, 2019Primary Objective: Randomised arm: To compare Long-term pain Response after dose- intensified imageguide hypofractioned SBRT employing SIB versus conventional Radiation therapy for painful spinal metastasis Prospective observational arm: To assess t...
Clinical Studies - Jul 3, 2019 - Jul 3, 2024
Ongoing
Project leader: Henke Guido
Members: Panje Cédric, Glatzer Markus
EORTC 1702-LCG-ROG Targeted therapy with or without dose-intensified radiotterapy in oligo-progressive disease (OPD) in oncogene Addicted Lung Tumors
Jun 12, 2019Targeted therapy beyond Progression with or without dose-intensified radiotHerapy in oligo-progressive disease (OPD) in oncogene Addicted Lung Tumors (HALT) Objectives: To determine wether in patients with Mutation positive advanced NSCLC the use of...
Clinical Studies - Jun 12, 2019 - Feb 1, 2021
Automatically Closed
Project leader: Glatzer Markus
STORM: A randomized phase II Trial for the Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases
Jun 1, 2019To compare metastases-free survival (MFS) between metastasis-directed therapy and metastases-directed therapy with whole pelvis radiotherapy for oligorecurrent nodal prostate cancer. Target: 178 Patients
Clinical Studies - Jun 1, 2019 - Jul 1, 2025
Ongoing
Project leader: Putora Paul Martin
Decision Making in Oncology - Transfer of Competencies between HSG-KSSG
Mar 1, 2018Decision making in medicine is a very complex process and of central importance to the patient and physician in oncology. Our previous work (based at KSSG) has demonstrated a wide variability in expert decision making in oncology (including the use o...
Fundamental Research - Mar 1, 2018 - Dec 31, 2020
Automatically Closed
Project leader: Putora Paul Martin
SAKK 08/15 PROMET
Sep 27, 2017PROMET - Multicenter, Randomized Phase II Trial of Salvage Radiotherapy +/- Metformin for Patients with Prostate Cancer after Prostatectomy The main objective of the trial is to explore the efficacy of SRT plus metformin compared to SRT in the endpo...
Clinical Studies - Sep 27, 2017 - Oct 7, 2030
Ongoing
Project leader: Putora Paul Martin
Members: Panje Cédric
Impact of Sarcopenia in Curative Trimodality Therapy for Esophageal Cancer
Jan 13, 2015The aim of the study is to investigate the prevalence and course of sarcopenia in patients undergoing curative trimodality therapy for locally advanced esophageal cancer and to correlate skeletal muscle mass with treatment complications during neoadj...
Clinical Studies - Jan 13, 2015 - Dec 31, 2015
Automatically Closed
Project leader: Panje Cédric, Henke Guido
Members: Blum David
SAKK 63/12 Prospective cohort study with collection of clinical data and serum of patients with prostate disease
Oct 15, 2014Diese Studie umfasst die Erstellung einer Serum- und Gewebebank, sowie die Erhebung zugehöriger klinischer Daten.
Clinical Studies - Oct 15, 2014 - Oct 15, 2024
Ongoing
Project leader: Engeler Daniel, Gillessen Sommer Silke
Members: Rothermundt Christian, Omlin Aurelius, Putora Paul Martin, Lengwiler Daniel, Patzl Sigrid, Schaepper Sibylle, Schwab Christoph, Abt Dominik, Templeton Arnoud
Prostatic Artery Embolization vs. conventional TUR-P in the Treatment of Benign Prostatic Hyperplasia: A prospective randomized trial
Feb 5, 2014
Clinical Studies - Feb 5, 2014 - Apr 5, 2023
Automatically Closed
Project leader: Engeler Daniel, Abt Dominik
Members: Schmid Hans-Peter, Hechelhammer Lukas, Patzl Sigrid, Lengwiler Daniel, Haile Sarah, Maier Reinhard, Schulz Thomas
Integrative Translational Research Network for Lung Cancer (ITRNLC)
Oct 1, 2012Lung cancer remains a health issue with a dismal outcome and evolution in the search of new prognostic markers and therapeutic approaches. To improve research efforts interdisciplinary and multicenter research networks are needed. For competitive tra...
Fundamental Research - Oct 1, 2012 - Dec 31, 2015
Completed
Project leader: Brutsche Martin, Putora Paul Martin
Members: Baty Florent
Avastin plus Radiotherapy in Elderly Patients with Glioblastoma (ARTE) A phase II, randomized, parallel-group, explorative, open labeled multi-center study of bevacizumab (Avastin®) in elderly subjects with newly diagnosed glioblastoma
Aug 17, 2012Die Prognose von Patienten, die an einem Glioblastom erkranken, ist sehr schlecht, insbesondere bei älteren Patienten. Derzeit gilt die Strahlentherapie als Standardtherapie nach der Operation mit einer medianen Überlebenszeit von etwa 6 Monaten. Ein...
Clinical Studies - Aug 17, 2012 - May 30, 2015
Completed
Project leader: Plasswilm Ludwig
Members: Weder Patrik, Hundsberger Thomas
Carboplatin chemotherapy and involved node radiotherapy in stage II A
Apr 24, 2012Testing efficacy and safety of carboplain chemotherapy and involved node Radio Therapy in patients with stage II A/B seminoma.
Clinical Studies - Apr 24, 2012 - Jun 5, 2028
Ongoing
Project leader: Plasswilm Ludwig
Quality Assurance of Prostate Cancer Radiotherapy Guidelines
Apr 5, 2012The aim of our project is the comparison of guidelines for the primary radiotherapy of prostate cancer among institutions in Switzerland. The goal is not the leveling of guidelines, but a neutral description of deviations, which may lead to a critic...
Clinical Studies - Apr 5, 2012 - Apr 5, 2013
Automatically Closed
Project leader: Putora Paul Martin
Members: Plasswilm Ludwig, Horstkemper Ruth