SWISS-AF Burden
abstract |
Health consequences of the Burden of atrial fibrillation The added information of measuring AF burden andmeasuring cardiac dimensions and function in an AF patient population where brain MRIs are available, could provide further evidence towards a better understanding of the correlation between AF and stroke. Prospective Holter data and continuous monitoring with implantable devices in unselected AF populations are scarce and the clinical relevance of a potential decrease in AF burden has not been described yet. Holter monitoring at baseline and one year thereafter in the whole Swiss-AF BURDEN cohort and continuous rhythm monitoring in a subgroup with implantable loop recorders (ILR) will allow us to 1.) precisely assess the time in AF and 2.) to assess the change in AF burden during prospective follow-up. This is important as it remains currently unknown whether a clear threshold exists or whether the risk of stroke and other adverse outcome events increases continuously with increasing AF burden. We have started Swiss-AF-BURDEN with a pilot study (Swiss-AFBURDEN Pilot study) that showed feasibility. The aim of this study is to increase our knowledge on the association between AF burden, change in AF burden and its health consequences, mainly stroke, systemic embolism and cognitive dysfunction |
project partner | Universitätsspital Basel |
type of project | clinical studies |
status | ongoing - follow up |
start of project | 2020 |
study design | prospective, multicenter, observational cohort study |
responsible person | Prof. Peter Ammann |