Publication

Argon beam coagulation for treatment of symptomatic radiation-induced proctitis

Journal Paper/Review - Apr 1, 1999

Units
PubMed

Citation
Fantin A, Binek J, Suter W, Meyenberger C. Argon beam coagulation for treatment of symptomatic radiation-induced proctitis. Gastrointestinal endoscopy 1999; 49:515-8.
Type
Journal Paper/Review (English)
Journal
Gastrointestinal endoscopy 1999; 49
Publication Date
Apr 1, 1999
Issn Print
0016-5107
Pages
515-8
Brief description/objective

BACKGROUND: Radiation proctitis is a complication of radiotherapy for malignant pelvic disease. Argon beam coagulation is a new and rapidly evolving technology that permits a "no-touch" electrocoagulation of diseased tissue. METHODS: We analyzed retrospectively the records of 7 patients with prostatic and endometrial cancers treated with irrradiation (median radiation dose was 6840 cGy, range 2400 to 7200 cGy). The median time to onset of symptoms after the conclusion of radiotherapy was 20 months (range 16 to 48 months); symptoms consisted of rectal bleeding and tenesmus in all patients. The patients underwent argon beam coagulation after colonoscopic evaluation. The usual treatment interval was 3 weeks (range 1 to 3 weeks). RESULTS: A median of 2 treatment sessions (range 2 to 4) was necessary for complete symptom relief. All interventions were well tolerated without complications. During follow-up (median 24 months, range 18 to 24 months), there was no recurrence of symptoms (bleeding, tenesmus). CONCLUSIONS: Argon beam coagulation is a safe, well tolerated, and effective treatment option in symptomatic radiation proctitis.