Kantonsspital St.Gallen

The impact of osteoporosis on adult deformity surgery outcomes in Medicare patients

Kunal Varshneya, Anika Bhattacharjya, Rayyan T Jokhai, Parastou Fatemi, Zachary A Medress, Martin N. Stienen, Allen L Ho, John K Ratliff & Anand Veeravagu


To identify the impact of osteoporosis (OS) on postoperative outcomes in Medicare patients undergoing ASD surgery.

Patients with OP and advanced age experience higher than average rates of ASD. However, poor bone density could undermine the durability of a deformity correction.

We queried the MarketScan Medicare Supplemental database to identify patients Medicare patients who underwent ASD surgery from 2007 to 2016.

A total of 2564 patients met the inclusion criteria of this study, of whom n = 971 (61.0%) were diagnosed with osteoporosis. Patients with OP had a similar 90-day postoperative complication rates (OP: 54.6% vs. non-OP: 49.2%, p = 0.0076, not significant after multivariate regression correction). This was primarily driven by posthemorrhagic anemia (37.6% in OP, vs. 33.1% in non-OP). Rates of revision surgery were similar at 90 days (non-OP 15.0%, OP 16.8%), but by 2 years, OP patients had a significantly higher reoperation rate (30.4% vs. 22.9%, p < 0.0001). In multivariate regression analysis, OP increased odds for revision surgery at 1 year (OR 1.4) and 2 years (OR 1.5) following surgery (all p < 0.05). OP was also an independent predictor of readmission at all time points (90 days, OR 1.3, p < 0.005).

Medicare patients with OP had elevated rates of complications, reoperations, and outpatient costs after undergoing primary ASD surgery.
citation Varshneya K, Bhattacharjya A, Jokhai R T, Fatemi P, Medress Z A, Stienen M N, Ho A L, Ratliff J K, Veeravagu A. The impact of osteoporosis on adult deformity surgery outcomes in Medicare patients. Eur Spine J 2021;.
type journal paper/review (English)
date of publishing 16-10-2021
journal title Eur Spine J
ISSN electronic 1432-0932
PubMed 34655336
DOI 10.1007/s00586-021-06985-z