Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis

Publication

Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis

Journal Paper/Review - Oct 12, 2005

Engelter S T, Bogousslavsky J, Sztajzel R, Baumgartner R W, Hungerbühler H J, Tettenborn Barbara, Mattle H P, Michel P, Arnold M, Lüthy R, Müller F, Weder B, Baumann A, Georgiadis D, Sekoranja L, Reichhart M, Lyrer P A

Citation

Engelter S, Bogousslavsky J, Sztajzel R, Baumgartner R, Hungerbühler H, Tettenborn B, Mattle H, Michel P, Arnold M, Lüthy R, Müller F, Weder B, Baumann A, Georgiadis D, Sekoranja L, Reichhart M, Lyrer P. Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis. Neurology 2005; 65:1795-8.

Type

Journal Paper/Review (English)

Journal

Neurology 2005; 65

Publication Date

Oct 12, 2005

Issn Electronic

1526-632X

Pages

1795-8

Brief description/objective

This databank-based, multicenter study compared all stroke patients with IV tissue plasminogen activator aged > or = 80 years (n = 38) and those < 80 years old (n = 287). Three-month mortality was higher in older patients. Favorable outcome (modified Rankin scale < or = 1) and intracranial hemorrhage (asymptomatic/symptomatic/fatal) were similarly frequent in both groups. Logistic regression showed that stroke severity, time to thrombolysis, glucose level, and history of coronary heart disease independently predicted outcome, whereas age did not.