The role of neoadjuvant chemotherapy and interval laparotomy in advanced ovarian cancer

Publication

The role of neoadjuvant chemotherapy and interval laparotomy in advanced ovarian cancer

Journal Paper/Review - Mar 1, 2002

Huober Jens, Meyer A, Wagner U, Wallwiener D

Citation

Huober J, Meyer A, Wagner U, Wallwiener D. The role of neoadjuvant chemotherapy and interval laparotomy in advanced ovarian cancer. Journal of cancer research and clinical oncology 2002; 128:153-60.

Type

Journal Paper/Review (English)

Journal

Journal of cancer research and clinical oncology 2002; 128

Publication Date

Mar 1, 2002

Issn Print

0171-5216

Pages

153-60

Brief description/objective

Radical debulking surgery allows for optimal cytoreduction in less than 50% of patients with advanced ovarian cancer. In spite of highly efficient chemotherapeutic regimens, the prognosis of patients with residual tumor masses larger than 1 cm in diameter following staging laparotomy is very poor. This observation led to the initiation of numerous trials evaluating the feasibility and efficiency of the use of primary chemotherapy followed by interval laparotomy in women with advanced ovarian cancer. The available data is presented and discussed in this review.