Publication

Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Journal Paper/Review - Nov 18, 2019

Units
PubMed
Doi

Citation
Anthis A, Chavatte-Palmer P, Jochum W, Wick P, Dommann A, Bürki-Turnherr T, Fischer T, Hornung R, Bertazzo S, Lehner S, Wildermuth S, Leschka S, Tsolaki E, Didierlaurent L, Staubli S, Zboray R, Neels A, Dietrich D, Manser P, Desbiolles L, Herrmann I. Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure. Analyst 2019; 144:6850-6857.
Type
Journal Paper/Review (English)
Journal
Analyst 2019; 144
Publication Date
Nov 18, 2019
Issn Electronic
1364-5528
Pages
6850-6857
Brief description/objective

Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.