Treatments of osteoporosis increase bone material strength index in patients with low bone mass
Manuela Schöb, F Malgo, J J M Peeters, E M Winter, S E Papapoulos & N M Appelman-Dijkstra
Effects on bone material properties of two-year antiosteoporotic treatment were assessed using in vivo impact microindentation (IMI) in patients with low bone mineral density (BMD) values. Antiresorptive treatment, in contrast to vitamin D ± calcium treatment alone, induced BMD-independent increases in bone material strength index, measured by IMI, the magnitude of which depended on pretreatment values.
In patients at increased fracture risk, antiresorptive treatments induced BMD-independent increases in BMSi values, the magnitude of which depended on pretreatment values.
|citation||Schöb M, Malgo F, Peeters J J M, Winter E M, Papapoulos S E, Appelman-Dijkstra N M. Treatments of osteoporosis increase bone material strength index in patients with low bone mass. Osteoporos Int 2020;.|
|type||journal paper/review (English)|
|date of publishing||08-04-2020|
|journal title||Osteoporos Int|