Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of Growth Factors and Drugs
Anke Bernstein, Norbert P Suedkamp, Hermann O Mayr, Steffen Kissling & Michael Seidenstuecker
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abstract
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In this present work we could show that a microporous β-TCP
ceramic with interconnected porosity and 5 μm median pore
diameter is a useful delivery vehicle for drugs and growth factors.
However, it is necessary to combine the ceramics with degradable
biopolymers, like hydrogels for retarded release. So the drug
release could be increased by the factor 7 from 3 up to 21 days with
concentrations having an antimicrobial activity. Concerning the
growth factor, the release period was prolonged significantly.
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citation
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Bernstein A, Suedkamp N P, Mayr H O, Kissling S, Seidenstuecker M.
Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of
Growth Factors and Drugs. Key Engineering Materials 2013;93-96.
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type
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journal paper/review (English)
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date of publishing
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11-2013
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journal title
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Key Engineering Materials (587)
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pages
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93-96
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contact
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Steffen Kissling
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