Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries

Publication

Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries

Journal Paper/Review - Dec 15, 2004

Hoffmann Rainer, Weber Christian, Langenberg Roswitha, Franke Andreas, Iofina Ekatarina, Blindt Rüdiger, Haager Philipp K., Ortlepp Jan R, Radke Peter W, Hanrath Peter

Citation

Hoffmann R, Weber C, Langenberg R, Franke A, Iofina E, Blindt R, Haager P, Ortlepp J, Radke P, Hanrath P. Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries. The American journal of cardiology 2004; 94:1548-50.

Type

Journal Paper/Review (English)

Journal

The American journal of cardiology 2004; 94

Publication Date

Dec 15, 2004

Issn Print

0002-9149

Pages

1548-50

Brief description/objective

Intravascular ultrasound studies were performed at angiographic follow-up on 121 native coronary lesions treated with 1 bare metal stent (n = 50), high-dose dexamethasone-eluting stents (n = 18), non-polymer-based paclitaxel-eluting stents (n = 18), or sirolimus-eluting stents (n = 35). Paclitaxel- and sirolimus-eluting stents reduced mean intimal hyperplasia thickness compared with bare metal stents by 49% and 90% (p = 0.048 and p <0.001), respectively, whereas mean intimal hyperplasia thickness treated with dexamethasone-eluting stents was similar to those lesions treated with bare metal stents.