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Cardiac resynchronization therapy in chronic heart failure

Christian Sticherling, Beat Schaer, Martin Coenen, Michael Kühne, Peter Ammann & Stefan Osswald

abstract Cardiac resynchronisation therapy (CRT) has emerged as a treatment option for patients with severe, drug-refractory heart failure and signs of intraventricular dyssynchrony. In clinical trials CRT reduced the overall mortality, improved symptoms, exercise tolerance, and left ventricular function, as compared with optimised medical therapy alone. One of the challenging fields in patient selection for CRT is to identify the 20-30% of heart failure patients with bundle branch block that will not respond to this novel therapy. Other fields of uncertainty, such as CRT in patients with atrial fibrillation or chronic right ventricular stimulation as well as the role of a back-up defibrillator will be discussed.
   
citation Sticherling C, Schaer B, Coenen M, Kühne M, Ammann P, Osswald S. Cardiac resynchronization therapy in chronic heart failure. Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2006; 136:611-7.
   
type journal paper/review (English)
date of publishing 30-9-2006
journal title Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology (136/39-40)
ISSN print 1424-7860
pages 611-7
PubMed 17086506
DOI 2006/39/smw-11597