[Diagnosis of malignant bone and soft tissue tumors]
H Rechl, C Kirchhoff, K Wörtler, U Lenze, Andreas Toepfer & R Von Eisenhart-Rothe
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abstract
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Primary sarcoma of bone is a rare entity but nevertheless a
significant cause of mortality in children and adolescents. The
focus of the preoperative evaluation is to set up a histological
diagnosis, define local tumor extent and develop a therapy regimen.
In addition to patient history and clinical findings a radiograph in
two orthogonal planes is still of great importance. MRI plays a
major role in the further clarification of the diagnosis, while CT
is valuable in the diagnosis of tumors of the axial skeleton as well
as in systemic staging. A PET-CT can be performed to obtain an
overview of further tumor sites. Open bone biopsy is the final
diagnostic step and should be carried out at the institution where
the definitive treatment will be performed. Complications such as
fracture, neural lesions and spread of tumor cells are relatively
rare if the biopsy is performed appropriately; however, patients
should be instructed to strictly avoid weight-bearing on the
affected extremity.
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citation
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Rechl H, Kirchhoff C, Wörtler K, Lenze U, Toepfer A, von
Eisenhart-Rothe R. [Diagnosis of malignant bone and soft tissue
tumors]. Orthopade 2011; 40:931-41; quiz 942-3.
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type
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journal paper/review (Translation2::getLang(): unknown language "".
Use Translation2::setLang() to set a default language.)
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date of publishing
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10-2011
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journal title
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Orthopade (40/10)
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ISSN electronic
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1433-0431
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pages
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931-41; quiz 942-3
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PubMed
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21874363
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DOI
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10.1007/s00132-011-1821-7
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