Significant prevalence of peripheral artery disease in patients with disturbed wound healing following elective foot and ankle surgery: Results from the ABI-PRIORY (ABI as a PRedictor of Impaired wound healing after ORthopedic surgerY) trial
Arne M Müller, Andreas Toepfer, Norbert Harrasser, Bernhard Haller, Markus Walther, Rüdiger Von Eisenhart-Rothe, Karla Gemperlein, Katharina Bergmann, Christian Bradaric, Karl-Ludwig Laugwitz, Tareq Ibrahim & Ralf J Dirschinger
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abstract
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Disturbed wound healing (DWH) following elective foot and ankle
surgery is associated with a number of known risk factors. The
purpose of this study was to determine if peripheral artery disease
(PAD) is a potential risk factor that contributes to an increase in
postoperative DWH. In a case-control study, we analyzed all patients
undergoing elective foot and ankle surgery between January 1, 2014
and December 31, 2017 at two institutions and identified 51 patients
with postoperative DWH. After matching with 51 control patients
without DWH, all 102 patients were evaluated for PAD. The prevalence
of PAD was significantly higher in the DWH group compared to the
control group (41.2% vs 19.6%, < 0.01). This difference was even
more distinctive for patients with any abnormal ankle-brachial index
(ABI) (51.0% vs 19.6%, < 0.001). After adjustment for diabetes,
hypertension, hypercholesterolemia, and smoking, any abnormal ABI or
a history of PAD remained an independent risk factor for DWH (odds
ratio 3.28; 95% CI 1.24-8.71). In this dual-center study,
postoperative DWH was associated with significantly higher rates of
PAD. These findings suggest that preoperative evaluation for PAD
could be a helpful tool to identify patients at high risk for
postoperative wound complications undergoing foot and ankle surgery.
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citation
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Müller A M, Toepfer A, Harrasser N, Haller B, Walther M, von
Eisenhart-Rothe R, Gemperlein K, Bergmann K, Bradaric C, Laugwitz K
L, Ibrahim T, Dirschinger R J. Significant prevalence of peripheral
artery disease in patients with disturbed wound healing following
elective foot and ankle surgery: Results from the ABI-PRIORY (ABI as
a PRedictor of Impaired wound healing after ORthopedic surgerY)
trial. Vasc Med 2019; 25:118-123.
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type
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journal paper/review (English)
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date of publishing
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15-11-2019
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journal title
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Vasc Med (25/2)
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ISSN electronic
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1477-0377
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pages
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118-123
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PubMed
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32366205
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DOI
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10.1177/1358863X19883945
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contact
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Vilijam Zdravkovic
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