Publication
Prospective and retrospective ECG-gating for CT coronary angiography perform similarly accurate at low heart rates
Journal Paper/Review - Jan 14, 2010
Stolzmann Paul, Alkadhi Hatem, Marincek Borut, Feuchtner Gudrun, Scheffel Hans, Falk Volkmar, Plass André, Baumueller Stephan, Goetti Robert, Leschka Sebastian
Units
PubMed
Doi
Citation
Type
Journal
Publication Date
Issn Electronic
Brief description/objective
OBJECTIVE: To compare, in patients with suspicion of coronary artery disease (CAD) and low heart rates, image quality, diagnostic performance, and radiation dose values of prospectively and retrospectively electrocardiography (ECG)-gated dual-source computed tomography coronary angiography (CTCA) for the diagnosis of significant coronary stenoses. MATERIALS AND METHODS: Two-hundred consecutive patients with heart rates 0.05). There was no significant difference in the rate of non-assessable coronary segments between group 1 (1.6%, 24/1404) and group 2 (1.4%, 19/1385; p=0.77); non-diagnostic image quality was significantly (p<0.001) more often attributed to stair step artifacts in group 1. Segment-based sensitivity, specificity, PPV, NPV, and accuracy were 98%, 98%, 88%, 100%, and 100% among group 1; 96%, 99%, 90%, 100%, and 98% among group 2, respectively. Parameters of diagnostic performance were similar (all p>0.05). Mean effective radiation dose of prospectively ECG-gated CTCA (2.2+/-0.4mSv) was significantly (p<0.0001) smaller than that of retrospectively ECG-gated CTCA (8.1+/-0.6mSv). CONCLUSION: Prospectively ECG-gated CTCA yields similar image quality, performs as accurately as retrospectively ECG-gated CTCA in patients having heart rates