Kantonsspital St.Gallen

The heart of patients with aortic aneurysms: evidence from cardiac computed tomography

Paul Stolzmann, Catherine Phan, Lotus Desbiolles, Mario Lachat, Thomas Pfammatter, Borut Marincek, Mathias Prokop & Hatem Alkadhi

abstract To determine in patients with abdominal aortic aneurysm (AAA) the coronary calcium burden and prevalence of coronary artery disease (CAD) in relation to cardiovascular risk factors, and to assess the left ventricular (LV) function using cardiac computed tomography (CT). Sixty consecutive patients (six females; 72.2+/-9.0 years) with AAA underwent dual-source CT calcium scoring and coronary angiography prior to AAA repair. In the 60 patients, the Framingham risk score (FRS) ranged from 5-43%. Twenty patients (33%) were at low, 16 (27%) at intermediate, and 24 (40%) at high risk for cardiovascular disease. The median Agatston score (AS) was 393 (0-3538). No significant correlation was found between AS and FRS (P=0.76). 846/851 coronary segments (99%) in 57/60 patients (95%) were depicted with a diagnostic image quality. Significant stenoses were found in 132/846 segments (16%) in 33/60 patients (55%). Five patients (8%) with significant coronary artery stenosis showed reduced LV function [ejection fraction (EF)<50%]. The extent of CAD was significantly correlated with AS (r=0.43, P<0.01), whereas no correlation was found for FRS (P=0.55). Cardiac CT is feasible in patients with AAA and allows for the assessment of coronary calcium, coronary stenoses, and LV function. The calcium burden and coronary stenoses assessment with cardiac CT provides incremental information beyond traditional cardiovascular risk factors alone.
citation Stolzmann P, Phan C, Desbiolles L, Lachat M, Pfammatter T, Marincek B, Prokop M, Alkadhi H. The heart of patients with aortic aneurysms: evidence from cardiac computed tomography. Interact Cardiovasc Thorac Surg 2009; 9:769-73.
type journal paper/review (English)
date of publishing 25-08-2009
journal title Interact Cardiovasc Thorac Surg (9/5)
ISSN electronic 1569-9285
pages 769-73
PubMed 19706720
DOI 10.1510/icvts.2009.215145