Kantonsspital St.Gallen

[Interdisciplinary Management of Sellar Masses]

Barbara Bischofberger-Baumann, Andrea Ebert, Claudia Hader, Jeanyves Fournier & Stefan Bilz

abstract Interdisciplinary Management of Sellar Masses Sellar masses may present with an impairment of pituitary function (hypopituitarism), hormone hypersecretion (prolactinoma, acromegaly, glucocorticoid excess) or neurological symptoms (visual impairment, headache). An increasing number of them is discovered as an incidentaloma. Among the various entities, benign pituitary adenomas and cystic lesions are most frequently encountered. The work-up includes a laboratory evaluation for hormone hyper- or hyposecretion and an MRI of the pituitary gland. If the optic chiasm is compromised, a visual field examination is mandatory. Except for prolactinomas, symptomatic sellar masses are usually resected via an endoscopic transsphenoidal approach. If a total resection is not feasible because of the invasion of surrounding structures, debulking to relieve pressure from the optic chiasm is the primary goal and radiotherapy may be considered. Residual hormone excess can be treated medically. In the early postoperative period special attention to the development and treatment of disordered body water homeostasis and hypopituitarism is crucial. Interdisciplinary work-up and decision making are of utmost importance and will offer the best management.
citation Bischofberger-Baumann B, Ebert A, Hader C, Fournier J, Bilz S. [Interdisciplinary Management of Sellar Masses]. Praxis (Bern 1994) 2019; 108:599-608.
type journal paper/review (Translation2::getLang(): unknown language "". Use Translation2::setLang() to set a default language.)
date of publishing 7-2019
journal title Praxis (Bern 1994) (108/9)
ISSN print 1661-8157
pages 599-608
PubMed 31288663
DOI 10.1024/1661-8157/a003263