Trends in incidence of oesophageal and gastric cancer according to morphology and anatomical location, in Switzerland 1982-2011

Publication

Trends in incidence of oesophageal and gastric cancer according to morphology and anatomical location, in Switzerland 1982-2011

Journal Paper/Review - Dec 10, 2015

Feller Anita, Clough-Gorr Kerri M, Arndt Volker, Steiner Annik, Mousavi Mohsen, Frick Harald, Bouchardy Christine, Bordoni Andrea, Fehr Martin, The Nicer Working Group

Citation

Feller A, Clough-Gorr K, Arndt V, Steiner A, Mousavi M, Frick H, Bouchardy C, Bordoni A, Fehr M, The Nicer Working Group. Trends in incidence of oesophageal and gastric cancer according to morphology and anatomical location, in Switzerland 1982-2011. Swiss Med Wkly 2015; 145:w14245.

Type

Journal Paper/Review (English)

Journal

Swiss Med Wkly 2015; 145

Publication Date

Dec 10, 2015

Issn Electronic

1424-3997

Pages

w14245

Brief description/objective

QUESTION UNDER STUDY/PRINCIPLES
This study aimed to evaluate trends in the incidence of oesophageal and gastric cancer by anatomical location and histology using nationally representative Swiss data.

METHODS
We included all oesophageal and gastric cancers recorded in 10 Swiss population-based cancer registries 1982-2011. We calculated age-standardised incidence rates (ASIRs) per 100 000 person-years (PY) (European standard) for both cancer sites stratified by sex, language region (German, French-Italian), morphology and anatomical location. To assess time trends, we estimated annual percentage changes (APCs) with 95% confidence intervals (95% CIs).

RESULTS
ASIR of oesophageal adenocarcinoma increased in both sexes and language regions (p <0.001). The steepest increase occurred in males of the German-speaking region (APC 6.8%, 95% CI 5.8-7.8) with ASIRs of 0.8 per 100,000 PY in 1982-1987 and 3.9 per 100.000 PY in 2007-2011. Incidence of oesophageal squamous cell carcinoma decreased significantly in males of both language regions by around -1.5% per year. In contrast, a slight but significant increase (APC 1.4%, 95% CI 0.3-2.4]) of oesophageal squamous cell carcinoma was observed in females of the German-speaking region. We observed stable rates for cancer of the gastric cardia. The incidence of noncardia gastric cancer decreased substantially in both sexes and language regions (p <0.001).

CONCLUSION
In Switzerland, the incidence of oesophageal adenocarcinoma has risen whereas incidence of noncardia gastric cancer has decreased substantially as observed in other developed countries.