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The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts

Paul Martin Putora, Dirk De Ruysscher, Markus Glatzer, Joachim Widder, Paul Van Houtte, Esther G C Troost, Ben J Slotman, Sara Ramella, Christoph Pöttgen, Stephanie Peeters, Ursula Nestle, Fiona McDonald, Cecile Le Pechoux, Rafal Dziadziuszko, Jose Belderbos & Corinne Faivre-Finn

abstract

BACKGROUND
The role of prophylactic cranial irradiation (PCI) and thoracic radiotherapy (TRT) is unclear in resected small cell lung cancer (SCLC).

METHODS
Thirteen European radiotherapy experts on SCLC were asked to describe their strategies on PCI and TRT for patients with resected SCLC. The treatment strategies were converted into decision trees and analyzed for consensus and discrepancies.

RESULTS
For patients with resected SCLC and positive lymph nodes most experts recommend prophylactic cranial irradiation and thoracic radiotherapy. For elderly patients with resected node negative SCLC, most experts do not recommend thoracic radiotherapy or prophylactic cranial irradiation.

CONCLUSION
PCI and TRT are considered in patients with resected SCLC and these treatments should be discussed with the patient in the context of shared decision-making.
   
citation Putora P M, De Ruysscher D, Glatzer M, Widder J, Van Houtte P, Troost E G C, Slotman B J, Ramella S, Pöttgen C, Peeters S, Nestle U, McDonald F, Le Pechoux C, Dziadziuszko R, Belderbos J, Faivre-Finn C. The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts. Radiother Oncol 2019; 145:45-48.
   
type journal paper/review (English)
date of publishing 27-12-2019
journal title Radiother Oncol (145)
ISSN electronic 1879-0887
pages 45-48
PubMed 31887577
DOI 10.1016/j.radonc.2019.11.022