Publication

Cardiopulmonary exercise testing in mild heart failure: impact of the mode of exercise on established prognostic predictors

Journal Paper/Review - Jan 1, 2008

Units
PubMed
Doi

Citation
Maeder M, Wolber T, Ammann P, Myers J, Brunner-La Rocca H, Hack D, Riesen W, Rickli H. Cardiopulmonary exercise testing in mild heart failure: impact of the mode of exercise on established prognostic predictors. Cardiology 2008; 110:135-41.
Type
Journal Paper/Review (English)
Journal
Cardiology 2008; 110
Publication Date
Jan 1, 2008
Issn Electronic
1421-9751
Pages
135-41
Brief description/objective

OBJECTIVES: In patients with heart failure (HF), peak oxygen consumption (peak VO(2)), the relationship between minute ventilation and carbon dioxide production (VE/VCO(2) slope) and heart rate recovery (HRR) are established prognostic predictors. However, treadmill exercise has been shown to elicit higher peak VO(2) values than bicycle exercise. We sought to assess whether the VE/VCO(2) slope and HRR in HF also depend on the exercise mode. METHODS: Twenty-one patients with mild HF on chronic beta-blocker therapy underwent treadmill and bicycle cardiopulmonary exercise testing for measurement of peak VO(2) and the VE/VCO(2) slope. In patients with sinus rhythm (n = 16), HRR at 1 (HRR-1) and 2 min (HRR-2) after exercise termination was assessed. RESULTS: Peak VO(2) was higher during treadmill as compared with bicycle testing (21.7 +/- 4.6 vs. 19.6 +/- 3.4 ml/kg/min; p = 0.006). HRR-1 tended to be slower (15 bpm, interquartile range 8-19, vs. 18 bpm, interquartile range 11-22; p = 0.16), and HRR-2 was significantly slower after treadmill exercise (26 bpm, interquartile range 20-39, vs. 31 bpm, interquartile range 22-41; p = 0.04). In contrast, VE/VCO(2) slope values did not differ between the test modes (32.9 +/- 5.5 vs. 32.3 +/- 5.0; p = 0.56). CONCLUSIONS: In contrast to peak VO(2) and HRR, the VE/VCO(2) slope is not affected by the exercise mode in patients with mild HF.