Kantonsspital St.Gallen

Early glottic carcinoma: treatment according patient's preference?

Sandro Stöckli, Isabel Schnieper, Pia Huguenin & Stephan Schmid

abstract BACKGROUND: To analyze the results in early (stage I and II) glottic carcinoma of a single institution with a patient-oriented concept. METHODS: After diagnostic workup and multidisciplinary counseling, either radiotherapy or CO(2) laser surgery was chosen with respect to the patient's preference. RESULTS: Sixty-five patients underwent laser surgery and 75 had radiotherapy. For T1 tumors, the 5-year overall survival, disease-specific survival, and initial local control rate after laser surgery and radiotherapy were comparable (OS, 85% vs 88%; DSS, 96% vs 93%; LCR, 86% vs 85%). In contrast, initial local control for T2 tumors was significantly more favorable after surgery (OS, 83% vs 78%; DSS, 83% vs 88%; LCR, 89% vs 67%). Larynx preservation was significantly higher after surgery in T1 tumors (96% vs 82%) and in T2 tumors (89% vs 77%). CONCLUSIONS: Selection of the treatment modality according to patient's preference results in a comparable control of disease for T1 tumors. The initial local control for T2 tumors is significantly better after surgery. In both stages laser surgery warrants a better larynx preservation rate.
citation Stöckli S, Schnieper I, Huguenin P, Schmid S. Early glottic carcinoma: treatment according patient's preference?. Head & neck 2003; 25:1051-6.
type journal paper/review (English)
date of publishing 12-2003
journal title Head & neck (25/12)
ISSN print 1043-3074
pages 1051-6
PubMed 14648864
DOI 10.1002/hed.10323