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Increased 18F-FDG uptake mimicking thyroid cancer in a patient with Hashimoto's thyroiditis

Daniel T Schmid, Stefan Kneifel, Sandro Stöckli, Barbara-C Padberg, Griff Merrill & Gerhard W Goerres

abstract We report the case of a 68-year-old patient with a known paravertebral malignant schwannoma, sent to us for postoperative staging. A combined whole-body PET/CT scan showed only poor (18)F-fluorodeoxyglucose uptake in the region of the primary tumor but distinct increased fluorodeoxyglucose uptake in the left and right thyroid gland. Thyroid sonography showed two hypoechogenic nodules. Ultrasound-guided fine-needle aspiration biopsy of one nodule showed oxyphil transformed cells, compatible with malignancy. Based on these findings, the patient underwent a subtotal thyroidectomy. Histopathology of the specimen revealed a chronic follicular Hashimoto's thyroiditis. This case demonstrates that Hashimoto's thyroiditis can mimic thyroid cancer in PET but also in sonography and fine-needle aspiration biopsy.
   
citation Schmid D T, Kneifel S, Stöckli S, Padberg B C, Merrill G, Goerres G W. Increased 18F-FDG uptake mimicking thyroid cancer in a patient with Hashimoto's thyroiditis. European radiology 2003; 13:2119-21.
   
type journal paper/review (English)
date of publishing 9-2003
journal title European radiology (13/9)
ISSN print 0938-7994
pages 2119-21
PubMed 12928962
DOI 10.1007/s00330-002-1619-4